| Bacteriophage Applications in Bacterial Fish Diseases |
| Paper ID : 1121-ICIAQUA |
| Authors |
|
Mehran Ahmadpoor *1, hulya saygi2, mehdi soltani3 1Department of Aquaculture, Fish Diseases Unit, Ege University, Faculty of Fisheries, Izmir, Turkey. 2Department of Aquaculture, Faculty of Fisheries, Ege University, Izmir, Turkey. 3, Department of Aquatic Animal Health Faculty of Veterinary Medicine University of Tehran Tehran, Iran |
| Abstract |
| Abstract Purpose: Bacterial diseases can give rise to significant fish mortality rates and lead to substantial economic losses within the aquaculture industry. In this context, antibiotics are primarily employed for therapeutic intentions. When administered via feed, antibiotics that cannot be absorbed by the fish tend to accumulate at the pond's floor or within the cage. Concurrently, antibiotics that can be metabolized are released into the water through fecal matter. According to existing knowledge, the presence of antibiotic residues and antibiotic resistance genes (ARGs) represents a potential hazard to both the environment and human health, particularly when transmitted to humans through food or environmental exposure. Method: In this study, our objective is to assess the research conducted on the effectiveness of bacteriophages as potential substitutes for antibiotics in the treatment of different bacterial diseases. These targeted diseases comprise Pseudomonas, Aeromonas salmonicida, Lactococcus garviae, Streptococcus agalactiae, Vibrio alginolyticus, Vibrio harveyi, Edwardsiella tarda, and Flavobacterium psychrophilum. Results: The applications of bacteriophages in relation to bacterial fish diseases have garnered substantial attention in recent years. Conclusions: The results obtained indicate Phage morphology, host range, single-step growth, tolerance to environmental conditions, detailed genome analysis, and in vitro lysis effect are important considerations for selecting an ideal phage for treatment. The ideal phage should display complete lytic activity, effectively target various variants and serotypes of bacteria, demonstrate resistance to environmental conditions, and remain unaffected by antibiotics. It is crucial that phage applications avoid the transfer of virulence genes and interference with the activity of other phages, leading to inhibition. Furthermore, when multiple phages are administered as a phage cocktail, it is vital that they do not exhibit negative interactions with each other. |
| Keywords |
| Antimicrobial, Bacteriophage, Bacterial Fish Diseases |
| Status: Abstract Accepted (Poster Presentation) |